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Antikörper

PA Antibody, HRP conjugated

Produktgrößen
50 ug
£186,00
CSB-PA395880EB01ILR-50UG
100 ug
£334,00
CSB-PA395880EB01ILR-100UG
Über dieses Produkt
SKU:
CSB-PA395880EB01ILR
Zusätzliche Namen:
PAPolymerase acidic protein antibody; EC 3.1.-.- antibody; RNA-directed RNA polymerase subunit P2 antibody
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
HRP
Weitere Details:
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity. In addition of its function in viral transcription, PA also plays an essential role in viral RNA synthesis and promotes the formation of the trimeric polymerase complex.
Host:
Rabbit
Immunogen:
Recombinant Influenza A virus Polymerase acidic protein (1-716AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Virus
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody