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Antikörper

NS Antibody, Biotin conjugated

Produktgrößen
50 ug
£186,00
CSB-PA356065LD01IIE-50UG
100 ug
£334,00
CSB-PA356065LD01IIE-100UG
Über dieses Produkt
SKU:
CSB-PA356065LD01IIE
Zusätzliche Namen:
NS antibody; Non-structural protein 1 antibody; NS1 antibody; NS1A antibody
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Klonalität:
Polyclonal
Konjugat:
Biotin
Weitere Details:
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1. In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm. Cellular protein synthesis is thereby shut off very early after virus infection. Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
Host:
Rabbit
Immunogen:
Recombinant Influenza A virus Non-structural protein 1 protein (152-237AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Virus
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody