DAB2 Antibody
Produktgrößen
50 ul
£186,00
CSB-PA337435-50UL
100 ul
£334,00
CSB-PA337435-100UL
Über dieses Produkt
- SKU:
- CSB-PA337435
- Zusätzliche Namen:
- DAB2 antibody; DOC2 antibody; Disabled homolog 2 antibody; Adaptor molecule disabled-2 antibody; Differentially expressed in ovarian carcinoma 2 antibody; DOC-2 antibody; Differentially-expressed protein 2 antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human DAB2
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:DAB2-Antibody-11101182.html
