CDKN1A Antibody
Produktgrößen
50 ul
£186,00
CSB-PA297162-50UL
100 ul
£334,00
CSB-PA297162-100UL
Über dieses Produkt
- SKU:
- CSB-PA297162
- Zusätzliche Namen:
- CAP20 antibody; CDK-interacting protein 1 antibody; CDKI antibody; CDKN1 antibody; Cdkn1a antibody; CDN1A_HUMAN antibody; CIP1 antibody; Cyclin Dependent Kinase Inhibitor 1A antibody; Cyclin-dependent kinase inhibitor 1 antibody; Cyclin-dependent kinase inhibitor 1A (P21) antibody; Cyclin-dependent kinase inhibitor 1A (p21, Cip1) antibody; DNA Synthesis Inhibitor antibody; MDA-6 antibody; MDA6 antibody; Melanoma differentiation-associated protein 6 antibody; Melanoma differentiation-associated protein antibody; p21 antibody; P21 protein antibody; p21CIP1 antibody; p21Cip1/Waf1 antibody; p21WAF antibody; PIC1 antibody; SDI1 antibody; SLC12A9 antibody; WAF1 antibody; Wild type p53 activated fragment 1 (WAF1) antibody; Wild type p53 activated fragment 1 antibody; Wildtype p53-activated fragment 1 antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human CDKN1A
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:CDKN1A-Antibody-11099265.html
