CTNNB1 Antibody

Produktgrößen

100 ul

£332,00

CSB-PA284161-100UL

Über dieses Produkt

SKU:: CSB-PA284161
Zusätzliche Namen:: Catenin beta-1
Anwendung:: ELISA, Western Blot
Buffer:: Supplied at 0.7mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Klonalität:: Polyclonal
Weitere Details:: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to a region derived from 757-770 amino acids of Human Catenin beta-1
Isotyp:: IgG
Physischer Zustand:: Liquid
Aufreinigung:: Affinity Purified
Reaktivitäten:: Human, Mouse, Rat
Versandbedingungen:: Blue Ice
Lagerbedingungen:: -20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:: Cusabio
Typ:: Antibody: Polyclonal Antibody

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