Map2k5 Antibody
Produktgrößen
100 ul
£332,00
CSB-PA283905-100UL
Über dieses Produkt
- SKU:
- CSB-PA283905
- Zusätzliche Namen:
- Map2k5 antibody; Mek5 antibody; Mkk5 antibody; Prkmk5 antibody; Dual specificity mitogen-activated protein kinase kinase 5 antibody; MAP kinase kinase 5 antibody; MAPKK 5 antibody; EC 2.7.12.2 antibody; MAPK/ERK kinase 5 antibody; MEK 5 antibody
- Anwendung:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phospho-rylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resem-bles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphory-late ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7)phosphorylates and activates the JNK signal transduction pathway. Han, J., et al. 1996. J. Biol. Chem. 271: 2886-2891. Jiang, Y., et al. 1996. J. Biol. Chem. 271: 17920-17926. Tournier, C., et al. 1997. Proc. Natl. Acad. Sci. USA94: 7337-7442. Holland, P.M., et al. 1997. J. Biol. Chem. 272: 24994-24998.
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa. 311-315(K-T-Y-V-G ) derived from Rat MEK5.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:Map2k5-Antibody-11083273.html
