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Antikörper

PIAS3 Antibody

Produktgrößen
100 ul
£332,00
CSB-PA283252-100UL
Über dieses Produkt
SKU:
CSB-PA283252
Zusätzliche Namen:
E3 SUMO protein ligase PIAS 3 antibody; E3 SUMO protein ligase PIAS3 antibody; E3 SUMO-protein ligase PIAS3 antibody; FLJ14651 antibody; OTTHUMP00000015586 antibody; OTTHUMP00000015587 antibody; PIAS 3 antibody; Pias3 antibody; PIAS3 protein antibody; PIAS3_HUMAN antibody; Protein inhibitor of activated STAT 3 antibody; Protein inhibitor of activated STAT protein 3 antibody; Protein inhibitor of activated STAT3 antibody; Zinc finger MIZ type containing 5 antibody; ZMIZ 5 antibody; ZMIZ5 antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Jiang-Hong Man, Nucleic Acids Res., Nov 2006; 34: 5552 - 5566. Amir Sonnenblick, Mol. Cell. Biol., Dec 2004; 24: 10584 - 10592. Jianyin Long, PNAS, Jan 2004; 101: 99. Hyun Duk Jang, J. Biol. Chem., Jun 2004; 279: 24873 - 24880.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from Internal of Human PIAS3.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody