DUSP1 Antibody
Produktgrößen
50 ul
£186,00
CSB-PA259888-50UL
100 ul
£334,00
CSB-PA259888-100UL
Über dieses Produkt
- SKU:
- CSB-PA259888
- Zusätzliche Namen:
- CL 100 antibody; CL100 antibody; Dual Specificity Phosphatase 1 antibody; Dual specificity protein phosphatase 1 antibody; Dual specificity protein phosphatase hVH1 antibody; DUS1_HUMAN antibody; DUSP 1 antibody; Dusp1 antibody; HVH1 antibody; MAP kinase phosphatase 1 antibody; Mitogen-activated protein kinase phosphatase 1 antibody; MKP-1 antibody; MKP1 antibody; Protein tyrosine phosphatase CL100 antibody; Protein-tyrosine phosphatase CL100 antibody; PTPN10 antibody; Serine/threonine specific protein phosphatase antibody; VH1 antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human DUSP1
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:DUSP1-Antibody-11102903.html
