DEAF1 Antibody
Produktgrößen
50 ul
£186,00
CSB-PA234417-50UL
100 ul
£334,00
CSB-PA234417-100UL
Über dieses Produkt
- SKU:
- CSB-PA234417
- Zusätzliche Namen:
- Deaf1 antibody; DEAF1 transcription factor antibody; DEAF1_HUMAN antibody; Deformed epidermal autoregulatory factor 1 homolog antibody; Nuclear DEA1 related transcriptional regulator antibody; Nuclear DEAF-1-related transcriptional regulator antibody; NUDR antibody; SPN antibody; Suppressin antibody; Zinc finger MYND domain containing protein 5 antibody; Zinc finger MYND domain-containing protein 5 antibody; ZMYND5 antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- Suppressin, also known as DEAF1 (deformed epidermal autoregulatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regulator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human DEAF1
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:DEAF1-Antibody-11104612.html
