POLR3D Antibody
Produktgrößen
100 ul
£332,00
CSB-PA220762-100UL
Über dieses Produkt
- SKU:
- CSB-PA220762
- Zusätzliche Namen:
- POLR3D antibody; BN51 antibody; BN51T antibody; DNA-directed RNA polymerase III subunit RPC4 antibody; RNA polymerase III subunit C4 antibody; DNA-directed RNA polymerase III subunit D antibody; Protein BN51 antibody; RNA polymerase III 47 kDa subunit antibody; RPC53 homolog antibody
- Anwendung:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway By similarity. Ittmann M., Mol. Cell. Biol. 7:3386-3393(1987). Hu P., Mol. Cell. Biol. 22:8044-8055(2002). Kalnine N., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human RPC4.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:POLR3D-Antibody-11085855.html
