ACVR2B Antibody
Produktgrößen
50 ul
£186,00
CSB-PA206692-50UL
100 ul
£334,00
CSB-PA206692-100UL
Über dieses Produkt
- SKU:
- CSB-PA206692
- Zusätzliche Namen:
- Activin A receptor type IIB antibody; Activin receptor type 2B antibody; Activin receptor type IIB antibody; Activin receptor type-2B antibody; ActR IIB antibody; ACTR-IIB antibody; ActRIIB antibody; ACVR 2B antibody; ACVR2B antibody; AVR2B_HUMAN antibody; HTX4 antibody; MGC116908 antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human ACVR2B
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:ACVR2B-Antibody-11099147.html
