NUAK1 Antibody
Produktgrößen
50 ul
£186,00
CSB-PA203867-50UL
100 ul
£334,00
CSB-PA203867-100UL
Über dieses Produkt
- SKU:
- CSB-PA203867
- Zusätzliche Namen:
- NUAK1 antibody; ARK5 antibody; KIAA0537 antibody; OMPHK1 antibody; NUAK family SNF1-like kinase 1 antibody; EC 2.7.11.1 antibody; AMPK-related protein kinase 5 antibody; ARK5 antibody; Omphalocele kinase 1 antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- NUAK family SNF1-like kinase 1 also known as AMPK-related protein kinase 5 (ARK5) is an enzyme that in humans is encoded by the NUAK1 gene. Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human NUAK1
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:NUAK1-Antibody-11104197.html
