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Antikörper

ABI1 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA196653-50UL
100 ul
£334,00
CSB-PA196653-100UL
Über dieses Produkt
SKU:
CSB-PA196653
Zusätzliche Namen:
Abelson interactor 1 antibody; Abi-1 antibody; Abi1 antibody; ABI1_HUMAN antibody; Abl binding protein 4 antibody; Abl interactor 1 antibody; Abl interactor protein 1 antibody; Abl-binding protein 4 antibody; AblBP4 antibody; e3B1 antibody; Eps8 binding protein antibody; Eps8 SH3 domain binding protein antibody; Eps8 SH3 domain-binding protein antibody; Eps8-binding protein antibody; Hssh3bp1 antibody; Interactor protein AblBP4 antibody; NAP1 antibody; Nap1 binding protein antibody; Nap1-binding protein antibody; Nap1BP antibody; Spectrin SH3 domain binding protein 1 antibody; Spectrin SH3 domain-binding protein 1 antibody; SSH3BP antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14
Host:
Rabbit
Immunogen:
Synthetic peptide of Human ABI1
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody