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Antikörper

Grin2b Antibody

Produktgrößen
100 ul
£332,00
CSB-PA191146-100UL
Über dieses Produkt
SKU:
CSB-PA191146
Zusätzliche Namen:
Grin2bGlutamate receptor ionotropic antibody; NMDA 2B antibody; GluN2B antibody; Glutamate [NMDA] receptor subunit epsilon-2 antibody; N-methyl D-aspartate receptor subtype 2B antibody; NMDAR2B antibody; NR2B antibody
Anwendung:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death Kornau H.C., Schenker L.T., Kennedy M.B., Seeburg P.H.Science 269:1737-1740(1995) Kurschner C., Mermelstein P.G., Holden W.T., Surmeier D.J.Mol. Cell. Neurosci. 11:161-172(1998)
Host:
Rabbit
Immunogen:
Peptide sequence around aa.1250-1254(N-L-Y-D-I) derived from Human NMDANR2B Subunit.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody