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Antikörper

ARL6IP1 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA178890-50UL
100 ul
£334,00
CSB-PA178890-100UL
Über dieses Produkt
SKU:
CSB-PA178890
Zusätzliche Namen:
ADP ribosylation factor like 6 interacting protein antibody; ADP-ribosylation factor-like protein 6-interacting protein 1 antibody; Aip-1 antibody; Aip1 antibody; AR6P1_HUMAN antibody; ARL-6-interacting protein 1 antibody; ARL6 interacting protein 1 antibody; ARL6IP antibody; Arl6ip1 antibody; ARMER antibody; KIAA0069 antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
ARMER (apoptotic regulator in the membrane of the endoplasmic reticulum), also known as ADP-ribosylation-like factor 6-interacting protein 1 (ARL6IP1 or AIP1), is a multi-pass membrane protein that belongs to the Ras superfamily. It is expressed in brain, thymus, lung, bone marrow and, to a lesser extent, in spleen, kidney and liver. ARMER is not found in the heart and is found predominantly in early myeloid progenitor cells localizing to the intracytoplasmic membranes. It interacts with ARL6, inhibits caspase-9 activity by inhibiting proteolysis of downstream substrates (including LEHD-AFC, vimentin and caspase-3) and is down-regulated during myeloid differentiation. ARMER may play a role in membrane trafficking, protein transport or cell signaling during hematopoietic maturation.
Host:
Rabbit
Immunogen:
Fusion protein of Human ARL6IP1
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody