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Antikörper

HDAC4 Antibody, HRP conjugated

Produktgrößen
50 ug
£186,00
CSB-PA17884B0RB-50UG
100 ug
£334,00
CSB-PA17884B0RB-100UG
Über dieses Produkt
SKU:
CSB-PA17884B0RB
Zusätzliche Namen:
AHO3 antibody; BDMR antibody; EC 3.5.1.98 antibody; HA6116 antibody; HD 4 antibody; HD4 antibody; HDAC 4 antibody; HDAC A antibody; HDAC4 antibody; HDAC4_HUMAN antibody; HDACA antibody; Histone deacetylase 4 antibody; Histone Deacetylase A antibody; KIAA0288 antibody
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
HRP
Weitere Details:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Deacetylates HSPA1A and HSPA1B at 'Lys-77' leading to their preferential binding to co-chaperone STUB1 (PubMed:27708256).
Host:
Rabbit
Immunogen:
Recombinant Human Histone deacetylase 4 protein (1-227AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody