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Antikörper

Mmp13 Antibody, Biotin conjugated

Produktgrößen
50 ug
£186,00
CSB-PA17739D0RB-50UG
100 ug
£334,00
CSB-PA17739D0RB-100UG
Über dieses Produkt
SKU:
CSB-PA17739D0RB
Zusätzliche Namen:
Mmp13 antibody; Collagenase 3 antibody; EC 3.4.24.- antibody; Matrix metalloproteinase-13 antibody; MMP-13 antibody
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
Biotin
Weitere Details:
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
Host:
Rabbit
Immunogen:
Recombinant Mouse Collagenase 3 protein (105-472AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody