CMKLR1 Antibody
Produktgrößen
100 ul
£332,00
CSB-PA140333-100UL
Über dieses Produkt
- SKU:
- CSB-PA140333
- Zusätzliche Namen:
- CHEMERINR antibody; Chemokine like receptor 1 antibody; Chemokine-like receptor 1 antibody; CHEMR23 antibody; CMKLR1 antibody; CML1_HUMAN antibody; DEZ antibody; G protein coupled receptor ChemR23 antibody; G protein coupled receptor DEZ antibody; G-protein coupled receptor ChemR23 antibody; G-protein coupled receptor DEZ antibody; Orphan G protein coupled receptor antibody; Orphan G protein coupled receptor Dez antibody; Resolvin E1 receptor antibody; RVER1 antibody
- Anwendung:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). Methner A., Biochem. Biophys. Res. Commun. 233:336-342(1997). Samson M., Eur. J. Immunol. 28:1689-1700(1998). Hillman R.T., Genome Biol. 5:RESEARCH008.1-RESEARCH008.16(2004).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human CMKLR1.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:CMKLR1-Antibody-11085394.html
