HMGCS1 Antibody
Produktgrößen
50 ul
£186,00
CSB-PA133916-50UL
100 ul
£334,00
CSB-PA133916-100UL
Über dieses Produkt
- SKU:
- CSB-PA133916
- Zusätzliche Namen:
- 3 hydroxy 3 methylglutaryl Coenzyme A synthase 1 (soluble) antibody; 3-hydroxy-3-methylglutaryl coenzyme A synthase antibody; cytoplasmic antibody; EC 2.3.3.10 antibody; HMCS1_HUMAN antibody; HMG CoA synthase antibody; HMG-CoA synthase antibody; HMGCS antibody; HMGCS1 antibody; Hydroxymethylglutaryl CoA synthase, cytoplasmic antibody; Hydroxymethylglutaryl-CoA synthase antibody; MGC90332 antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- HMG-CoA Synthase exists as both a mitochondrial (mHMGCS) and cytoplasmic (cHMGCS) enzyme that condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The HMG-CoA produced by cHMGCS is transformed into mevalonate by HMG-CoA reductase, which starts isoprenoid biosynthesis. End products of the isoprenoid pathway include cholesterol, ubiquinone, dolichol, isopentenyl adenosine and farnesyl groups. mHMGCS, together with HMG-CoA Lyase, is responsible for ketone body biosynthesis. mHMGCS is expressed in liver and kidney. Fasting, cAMP and fatty acids increase the level of transcription of mHMGCS, while feeding and insulin repress it. A regulatory element within the mHMGCS promoter confers transcriptional regulation by PPAR, RXR, COUP-TF and HNF-4.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human HMGCS1
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:HMGCS1-Antibody-11104825.html
