Phospho-ALK (Tyr1096) Antibody
Produktgrößen
100 ul
£402,00
CSB-PA116393-100UL
Über dieses Produkt
- SKU:
- CSB-PA116393
- Zusätzliche Namen:
- Alk antibody; ALK tyrosine kinase receptor antibody; ALK/EML4 fusion gene; included antibody; ALK/NPM1 fusion gene; included antibody; ALK_HUMAN antibody; anaplastic lymphoma kinase (Ki-1) antibody; Anaplastic lymphoma kinase antibody; Anaplastic lymphoma kinase Ki1 antibody; anaplastic lymphoma receptor tyrosine kinase antibody; CD 246 antibody; CD246 antibody; CD246 antigen antibody; EC 2.7.10.1 antibody; Ki 1 antibody; Ki1 antibody; mutant anaplastic lymphoma kinase antibody; NBLST 3 antibody; NBLST3 antibody; Tcrz antibody; TFG/ALK antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- The 2;5 chromosomal translocation is frequently associated with anaplastic large cell lymphomas (ALCLs). The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the nucleophosmin (NPM) gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5. A recent study shows that the product of the NPM-ALK fusion gene is oncogenic. The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain. Morris S.W., Oncogene 14:2175-2188(1997). Morris S.W., Oncogene 15:2883-2883(1997). Iwahara T., Oncogene 14:439-449(1997).
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 1096 (P-N-Y(p)-C-F) derived from Human ALK.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:Phospho-ALK-Tyr1096-Antibody-11084179.html
