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Antikörper

CAV1 (Ab-14) Antibody

Produktgrößen
100 ul
£332,00
CSB-PA112716-100UL
Über dieses Produkt
SKU:
CSB-PA112716
Zusätzliche Namen:
BSCL3 antibody; CAV antibody; CAV1 antibody; CAV1_HUMAN antibody; caveolae protein, 22 kD antibody; caveolin 1 alpha isoform antibody; caveolin 1 beta isoform antibody; Caveolin 1 caveolae protein 22kDa antibody; Caveolin-1 antibody; Caveolin1 antibody; cell growth-inhibiting protein 32 antibody; CGL3 antibody; LCCNS antibody; MSTP085 antibody; OTTHUMP00000025031 antibody; PPH3 antibody; VIP 21 antibody; VIP21 antibody
Anwendung:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
The scaffolding protein encoded by Caveolin-1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (a and beta) are encoded by a single transcript from this gene. Zhang Y, et al. (2005) Mol Cell Proteomics. 4(9): 1240-1250. Labrecque L, et al. (2004) J Biol Chem. 279(50): 52132-52140. Fielding PE, et al. (2004) Biochemistry. 43(9): 2578-2586. Labrecque L, et al. (2003) Mol Biol Cell. 14(1): 334-347. Maggi D, et al. (2002) Biochem Biophys Res Commun. 295(5): 1085-1089.
Host:
Rabbit
Immunogen:
Peptide sequence around aa.12~16 (H-L-Y-T-V) derived from Human CAVEOLIN-1.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody