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Antikörper

APLF (Ab-116) Antibody

Produktgrößen
100 ul
£332,00
CSB-PA109959-100UL
Über dieses Produkt
SKU:
CSB-PA109959
Zusätzliche Namen:
2010301N04Rik antibody; AI452191 antibody; Aplf antibody; APLF_HUMAN antibody; Aprataxin and PNK-like factor antibody; Apurinic-apyrimidinic endonuclease APLF antibody; C2orf13 antibody; PNK and APTX like FHA protein antibody; PNK and APTX-like FHA domain-containing protein antibody; RGD1565557 antibody; XIP1 antibody; XRCC1 interacting protein 1 antibody; XRCC1-interacting protein 1 antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage. Saunders W.S., J. Cell Sci. 104:573-582(1993). Ye Q., J. Biol. Chem. 271:14653-14656(1996). Ye Q., J. Biol. Chem. 272:14983-14989(1997).
Host:
Rabbit
Immunogen:
Synthesized non-phosphopeptide derived from Human APLF around the phosphorylation site of serine 116 (R-N-S(p)-Q-V).
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody