PTAFR Antibody
Produktgrößen
50 ul
£186,00
CSB-PA109839-50UL
100 ul
£334,00
CSB-PA109839-100UL
Über dieses Produkt
- SKU:
- CSB-PA109839
- Zusätzliche Namen:
- OTTHUMP00000004041 antibody; OTTMUSP00000010350 antibody; PAF R antibody; PAF receptor antibody; PAF-R antibody; PAFr antibody; Platelet activating factor receptor antibody; Platelet-activating factor receptor antibody; PTAFR antibody; PTAFR_HUMAN antibody; RP23-470B20.1 antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human PTAFR
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PTAFR-Antibody-11103859.html
