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Antikörper

GNL3L Antibody

Produktgrößen
100 ul
£332,00
CSB-PA106099-100UL
Über dieses Produkt
SKU:
CSB-PA106099
Zusätzliche Namen:
GNL3LGuanine nucleotide-binding protein-like 3-like protein antibody
Anwendung:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. Ota T., Nat. Genet. 36:40-45(2004). Ross M.T., Nature 434:325-337(2005). The MGC Project Team; Genome Res. 14-2121-2127(2004).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human GNL3L.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody