PLEKHO1 Antibody
Produktgrößen
50 ul
£186,00
CSB-PA105837-50UL
100 ul
£334,00
CSB-PA105837-100UL
Über dieses Produkt
- SKU:
- CSB-PA105837
- Zusätzliche Namen:
- C-Jun-binding protein antibody; Casein kinase 2-interacting protein 1 antibody; CK2 interacting protein 1 antibody; CK2 interacting protein 1 HQ0024c protein antibody; CK2-interacting protein 1 antibody; CKIP 1 antibody; CKIP-1 antibody; CKIP1 antibody; JBP antibody; OC120 antibody; Osteoclast maturation associated gene 120 protein antibody; Osteoclast maturation-associated gene 120 protein antibody; PH domain-containing family O member 1 antibody; PKHO1_HUMAN antibody; Pleckstrin homology domain containing family O member 1 antibody; Pleckstrin homology domain-containing family O member 1 antibody; PLEKHO1 antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- Pleckstrin homology domain-containing family O member 1 is a protein that in humans is encoded by the PLEKHO1 gene.PLEKHO1 has been shown to interact with Casein kinase 2, alpha 1 and SMURF1.It plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). Appears to target ATM to the plasma membrane,and also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. The protein implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human PLEKHO1
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PLEKHO1-Antibody-11102762.html
