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Antikörper

CENPA Antibody

Produktgrößen
100 ul
£332,00
CSB-PA097091-100UL
Über dieses Produkt
SKU:
CSB-PA097091
Zusätzliche Namen:
CENP A antibody; CENP-A antibody; cenpa antibody; CENPA_HUMAN antibody; Centromere autoantigen A antibody; Centromere protein A 17kDa antibody; Centromere protein A antibody; Histone H3 like centromeric protein A antibody; Histone H3-like centromeric protein A antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro). Sullivan K.F., J. Cell Biol. 127:581-592(1994). Hillier L.W., Nature 434:724-731(2005). Shelby R.D., J. Cell Biol. 136:501-513(1997).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human CENPA.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody