CTTN (Ab-466) Antibody
Produktgrößen
100 ul
£332,00
CSB-PA095187-100UL
Über dieses Produkt
- SKU:
- CSB-PA095187
- Zusätzliche Namen:
- Amplaxin antibody; CTTN antibody; EMS 1 antibody; EMS1 antibody; FLJ34459 antibody; Mammary tumor and squamous cell carcinoma associated antibody; Oncogene EMS1 antibody; p80/85 src substrate antibody; Src substrate cortactin antibody; SRC8_HUMAN antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Cortactin is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. Luo C, et al. (2006) J Biol Chem ; 281(40):30081-30093 Head JA, et al. (2003) Mol Biol Cell ;14(8):3216-3229 Li Y, et al. (2000) J Biol Chem ; 275(47): 37187-37193 Kinley AW, et al. (2003) Curr Biol ; 13(5): 384-393
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.464~468 (P-V-Y-E-T) derived from Human CORTACTIN.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:CTTN-Ab-466-Antibody-11083111.html
