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Antikörper

PTK2 (Ab-576/577) Antibody

Produktgrößen
100 ul
£332,00
CSB-PA077952-100UL
Über dieses Produkt
SKU:
CSB-PA077952
Zusätzliche Namen:
FADK 1 antibody; FADK antibody; FAK related non kinase polypeptide antibody; FAK1 antibody; FAK1_HUMAN antibody; Focal adhesion kinase 1 antibody; Focal adhesion Kinase antibody; Focal adhesion kinase isoform FAK Del33 antibody; Focal adhesion kinase related nonkinase antibody; FRNK antibody; p125FAK antibody; pp125FAK antibody; PPP1R71 antibody; Protein phosphatase 1 regulatory subunit 71 antibody; Protein tyrosine kinase 2 antibody; Protein-tyrosine kinase 2 antibody; Ptk2 antibody; PTK2 protein tyrosine kinase 2 antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. Parsons, J.T. et al. (2000) Oncogene 19, 5606-5613. Schaller, M.D. et al. (1994) Mol. Cell. Biol. 14, 1680-1688. Chen, H.C. et al. (1996) J. Biol. Chem. 271, 26329-26334. Calalb, M.B. et al. (1995) Mol. Cell. Biol. 15, 954-963.
Host:
Rabbit
Immunogen:
Peptide sequence around aa.574~578/575~579 (T-Y-Y-K-A) derived from Human FAK.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody