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Antikörper

DKK1 Antibody, Biotin conjugated

Produktgrößen
50 ug
£186,00
CSB-PA06219D0RB-50UG
100 ug
£334,00
CSB-PA06219D0RB-100UG
Über dieses Produkt
SKU:
CSB-PA06219D0RB
Zusätzliche Namen:
Dickkopf 1 antibody; Dickkopf 1 homolog antibody; Dickkopf 1 like antibody; Dickkopf homolog 1 antibody; Dickkopf like protein 1 antibody; Dickkopf related protein 1 antibody; Dickkopf WNT signaling pathway inhibitor 1 antibody; Dickkopf-1 antibody; Dickkopf-related protein 1 antibody; DKK 1 antibody; Dkk-1 antibody; Dkk1 antibody; DKK1_HUMAN antibody; hDkk 1 antibody; hDkk-1 antibody; SK antibody
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
Biotin
Weitere Details:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Host:
Rabbit
Immunogen:
Recombinant Human Dickkopf-related protein 1 protein (33-266AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody