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Antikörper

ERP29 Antibody, HRP conjugated

Produktgrößen
50 ug
£186,00
CSB-PA05344B0RB-50UG
100 ug
£334,00
CSB-PA05344B0RB-100UG
Über dieses Produkt
SKU:
CSB-PA05344B0RB
Zusätzliche Namen:
ERP29 antibody; C12orf8 antibody; ERP28Endoplasmic reticulum resident protein 29 antibody; ERp29 antibody; Endoplasmic reticulum resident protein 28 antibody; ERp28 antibody; Endoplasmic reticulum resident protein 31 antibody; ERp31 antibody
Anwendung:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
HRP
Weitere Details:
Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI's thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.
Host:
Rabbit
Immunogen:
Recombinant Human Endoplasmic reticulum resident protein 29 protein (40-251AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody