AATF Antibody, Biotin conjugated
Produktgrößen
50 ug
£186,00
CSB-PA05264D0RB-50UG
100 ug
£334,00
CSB-PA05264D0RB-100UG
Über dieses Produkt
- SKU:
- CSB-PA05264D0RB
- Zusätzliche Namen:
- AATF antibody; AATF_HUMAN antibody; Apoptosis antagonizing transcription factor antibody; Apoptosis-antagonizing transcription factor antibody; BFR2 antibody; CHE 1 antibody; CHE1 antibody; DED antibody; Protein AATF antibody; Rb binding protein Che 1 antibody; Rb-binding protein Che-1 antibody
- Anwendung:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Protein AATF protein (6-294AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:AATF-AntibodyBiotin-conjugated-57866.html