Phospho-ARRB1 (Ser412) Antibody
Produktgrößen
100 ul
£402,00
CSB-PA045801-100UL
Über dieses Produkt
- SKU:
- CSB-PA045801
- Zusätzliche Namen:
- ARB1 antibody; ARR1 antibody; ARRB1 antibody; ARRB1_HUMAN antibody; Arrestin 2 antibody; Arrestin beta 1 antibody; Arrestin beta-1 antibody; Beta-arrestin-1 antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. Greg Buchanan. AACR Meeting Abstracts, Apr 2006; 2006: 430. D. Alex Groarke. Mol. Pharmacol., Feb 2001; 59: 375. Karen McConalogue. Mol. Biol. Cell, Aug 1998; 9: 2305. Maria Stella Lombardi. Stroke, Apr 2004; 35: 981 - 986.
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of Serine 412 (T-G-S(p)-P-Q) derived from Human Arrestin 1.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:Phospho-ARRB1-Ser412-Antibody-11084118.html
