GPR161 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA04114A0RB-50UG
100 ug
£334,00
CSB-PA04114A0RB-100UG
Über dieses Produkt
- SKU:
- CSB-PA04114A0RB
- Zusätzliche Namen:
- GPR161 antibody; G-protein coupled receptor 161 antibody; G-protein coupled receptor RE2 antibody
- Anwendung:
- ELISA, Immunofluorescence, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human G-protein coupled receptor 161 protein (1-28AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:GPR161-Antibody-1027369.html
