PAWR Antibody
Produktgrößen
100 ul
£332,00
CSB-PA041090-100UL
Über dieses Produkt
- SKU:
- CSB-PA041090
- Zusätzliche Namen:
- 2310001G03Rik antibody; PAR 4 antibody; PAR-4 antibody; Pawr antibody; PAWR_HUMAN antibody; PRKC Apoptosis WT1 Regulator antibody; PRKC apoptosis WT1 regulator protein antibody; Prostate apoptosis response 4 protein antibody; Prostate apoptosis response protein 4 antibody; prostate apoptosis response protein PAR-4 antibody; Transcriptional repressor Par-4-like protein PAWR antibody; Transcriptional repressor PAR4 antibody; WT1 Interacting Protein antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1. Hongzhe Li, J. Biol. Chem., Feb 2007; 282: 4943 - 4950. Wuhan Xiao, Cancer Res., Aug 2003; 63: 4698 - 4704. Thierry Virolle, J. Biol. Chem., Mar 2003; 278: 11802 - 11810. Derek J. Richard, Genes & Dev., Feb 2001; 15: 328.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Human prostate apoptosis response protein-4.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PAWR-Antibody-11084652.html
