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Antikörper

ALPL Antibody

Produktgrößen
50 ul
£186,00
CSB-PA034215-50UL
100 ul
£334,00
CSB-PA034215-100UL
Über dieses Produkt
SKU:
CSB-PA034215
Zusätzliche Namen:
AKP2 antibody; Alkaline phosphatase liver/bone/kidney antibody; Alkaline phosphatase liver/bone/kidney isozyme antibody; Alkaline phosphatase tissue nonspecific isozyme antibody; Alkaline phosphatase, tissue-nonspecific isozyme antibody; Alkaline phosphomonoesterase antibody; Alpl antibody; AP TNAP antibody; AP-TNAP antibody; APTNAP antibody; BAP antibody; FLJ40094 antibody; FLJ93059 antibody; Glycerophosphatase antibody; HOPS antibody; Liver/bone/kidney type alkaline phosphatase antibody; MGC161443 antibody; MGC167935 antibody; PHOA antibody; PPBT_HUMAN antibody; Tissue non specific alkaline phosphatase antibody; Tissue nonspecific ALP antibody; TNAP antibody; TNSALP antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.
Host:
Rabbit
Immunogen:
Fusion protein of Human ALPL
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody