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Antikörper

FZD6 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA032335-50UL
100 ul
£334,00
CSB-PA032335-100UL
Über dieses Produkt
SKU:
CSB-PA032335
Zusätzliche Namen:
Frizzled 6 seven transmembrane spanning receptor antibody; Frizzled drosophila homolog of 6 antibody; Frizzled family receptor 6 antibody; Frizzled homolog 6 (Drosophila) antibody; Frizzled homolog 6 antibody; Frizzled-6 antibody; Frizzled6 antibody; Fz 6 antibody; Fz-6 antibody; Fz6 antibody; FZD 6 antibody; Fzd6 antibody; FZD6_HUMAN antibody; Hfz 6 antibody; hFz6 antibody; NDNC10 antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human FZD6
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody