HOMER1 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA03007A0RB-50UG
100 ug
£334,00
CSB-PA03007A0RB-100UG
Über dieses Produkt
- SKU:
- CSB-PA03007A0RB
- Zusätzliche Namen:
- HOME1_HUMAN antibody; Homer antibody; HOMER 1A antibody; HOMER 1B antibody; HOMER 1C antibody; Homer homolog 1 (Drosophila) antibody; homer homolog 1 antibody; Homer protein homolog 1 antibody; homer scaffolding protein 1 antibody; Homer; Drosophila; homolog of; 1 antibody; Homer; neuronal immediate early gene; 1 antibody; Homer-1 antibody; Homer1 antibody; HOMER1A antibody; HOMER1B antibody; HOMER1C antibody; SYN47 antibody; Ves 1 antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development. Forms a high-order complex with SHANK1, which in turn is necessary for the structural and functional integrity of dendritic spines (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Homer protein homolog 1 protein (1-354AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:HOMER1-Antibody-157357.html
