PVR Antibody
Produktgrößen
50 ul
£186,00
CSB-PA019093ESR2HU-50UL
100 ul
£334,00
CSB-PA019093ESR2HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA019093ESR2HU
- Zusätzliche Namen:
- CD155 antibody; CD155 antigen antibody; FLJ25946 antibody; HVED antibody; mE4 antibody; NECL 5 antibody; Necl-5 antibody; Necl5 antibody; Nectin like 5 antibody; Nectin like protein 5 antibody; Nectin-like protein 5 antibody; Ortholog of mouse Tage4 antibody; Poliovirus receptor antibody; PVR antibody; PVR_HUMAN antibody; PVS antibody; Taa1 antibody; Tage 4 antibody; TAGE4 antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. Serves as a receptor for poliovirus attachment to target cells. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport.2 Publications
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Poliovirus receptor protein (220-345AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PVR-Antibody-11081936.html
