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Antikörper

PRNP Antibody, FITC conjugated

Produktgrößen
50 ug
£186,00
CSB-PA018739LC01HU-50UG
100 ug
£334,00
CSB-PA018739LC01HU-100UG
Über dieses Produkt
SKU:
CSB-PA018739LC01HU
Zusätzliche Namen:
Alternative prion protein, major prion protein antibody; AltPrP antibody; ASCR antibody; CD230 antibody; CD230 antigen antibody; CJD antibody; GSS antibody; KURU antibody; Major prion protein antibody; p27 30 antibody; PRIO_HUMAN antibody; Prion protein antibody; Prion related protein antibody; PRIP antibody; PRNP antibody; PrP antibody; PrP27 30 antibody; PrP27-30 antibody; PrP33-35C antibody; PrPC antibody; PrPSc antibody; Sinc antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Klonalität:
Polyclonal
Konjugat:
FITC
Weitere Details:
Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as a agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
Host:
Rabbit
Immunogen:
Recombinant Human Major prion protein (23-64AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody