PPP1CC Antibody, Biotin conjugated
Produktgrößen
50 ug
£186,00
CSB-PA018505LD01HU-50UG
100 ug
£334,00
CSB-PA018505LD01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA018505LD01HU
- Zusätzliche Namen:
- PP 1G antibody; PP-1G antibody; PP1C antibody; PP1G antibody; PP1G_HUMAN antibody; PP1gamma antibody; PPP 1G antibody; PPP1CC antibody; PPP1G antibody; Protein phosphatase 1; catalytic subunit; gamma isozyme antibody; Protein phosphatase 1C catalytic subunit antibody; Serine/threonine phosphatase 1 gamma antibody; Serine/threonine protein phosphatase PP1 gamma catalytic subunit antibody; Serine/threonine-protein phosphatase PP1-gamma catalytic subunit antibody
- Anwendung:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Serine/threonine-protein phosphatase PP1-gamma catalytic subunit protein (151-323AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PPP1CC-AntibodyBiotin-conjugated-11111944.html