PPID Antibody
Produktgrößen
50 ul
£186,00
CSB-PA018474ESR2HU-50UL
100 ul
£334,00
CSB-PA018474ESR2HU-100UL
Über dieses Produkt
- SKU:
- CSB-PA018474ESR2HU
- Zusätzliche Namen:
- 40 kDa peptidyl-prolyl cis-trans isomerase antibody; 40 kDa peptidyl-prolyl cis-trans isomerase D antibody; Cyclophilin related protein antibody; Cyclophilin-40 antibody; Cyclophilin-related protein antibody; CYP-40 antibody; CYP40 antibody; CYPD antibody; Estrogen receptor-binding cyclophilin antibody; Peptidyl-prolyl cis-trans isomerase D antibody; Peptidylprolyl isomerase D antibody; PPIase D antibody; Ppid antibody; PPID_HUMAN antibody; Rotamase antibody; Rotamase D antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines. May be involved in hepatitis C virus (HCV) replication and release.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Peptidyl-prolyl cis-trans isomerase D protein (161-370AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PPID-Antibody-11081304.html
