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Antikörper

PPID Antibody

Produktgrößen
50 ul
£186,00
CSB-PA018474ESR1HU-50UL
100 ul
£334,00
CSB-PA018474ESR1HU-100UL
Über dieses Produkt
SKU:
CSB-PA018474ESR1HU
Zusätzliche Namen:
40 kDa peptidyl-prolyl cis-trans isomerase antibody; 40 kDa peptidyl-prolyl cis-trans isomerase D antibody; Cyclophilin related protein antibody; Cyclophilin-40 antibody; Cyclophilin-related protein antibody; CYP-40 antibody; CYP40 antibody; CYPD antibody; Estrogen receptor-binding cyclophilin antibody; Peptidyl-prolyl cis-trans isomerase D antibody; Peptidylprolyl isomerase D antibody; PPIase D antibody; Ppid antibody; PPID_HUMAN antibody; Rotamase antibody; Rotamase D antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines. May be involved in hepatitis C virus (HCV) replication and release.
Host:
Rabbit
Immunogen:
Recombinant Human Peptidyl-prolyl cis-trans isomerase D protein (161-370AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody