PCGF2 Antibody, FITC conjugated
Produktgrößen
50 ug
£186,00
CSB-PA017606LC01HU-50UG
100 ug
£334,00
CSB-PA017606LC01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA017606LC01HU
- Zusätzliche Namen:
- DNA binding protein Mel 18 antibody; DNA-binding protein Mel-18 antibody; Mel 18 antibody; MGC10545 antibody; PCGF 2 antibody; PCGF2 antibody; PCGF2_HUMAN antibody; Polycomb group ring finger 2 antibody; Polycomb group RING finger protein 2 antibody; RING finger protein 110 antibody; RNF110 antibody; Zinc finger protein 144 antibody; ZNF 144 antibody; ZNF144 antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- FITC
- Weitere Details:
- Transcriptional repressor. Binds specifically to the DNA sequence 5'-GACTNGACT-3'. Has tumor suppressor activity. May play a role in control of cell proliferation and/or neural cell development. Regulates proliferation of early T progenitor cells by maintaining expression of HES1. Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Is not functionally redundant with BMI1; unlike BMI1 does not stimulate the E3 ubiquitin-protein ligase activity in a reconstituted PRC1-like complex (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Polycomb group RING finger protein 2 protein (103-316AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PCGF2-AntibodyFITC-conjugated-12553760.html