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Antikörper

NF2 Antibody, FITC conjugated

Produktgrößen
50 ug
£186,00
CSB-PA015741LC01HU-50UG
100 ug
£334,00
CSB-PA015741LC01HU-100UG
Über dieses Produkt
SKU:
CSB-PA015741LC01HU
Zusätzliche Namen:
ACN antibody; BANF antibody; Bilateral acoustic neuroma antibody; MERL_HUMAN antibody; Merlin antibody; Moesin ezrin radixin like protein antibody; Moesin ezrin radizin like antibody; Moesin-ezrin-radixin-like protein antibody; Neurofibromatosis 2 antibody; Neurofibromatosis type 2 antibody; Neurofibromatosis2 antibody; Neurofibromin 2 antibody; Neurofibromin-2 antibody; Neurofibromin2 antibody; NF 2 antibody; Nf2 antibody; SCH antibody; Schwannomerlin antibody; Schwannomin antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Klonalität:
Polyclonal
Konjugat:
FITC
Weitere Details:
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
Host:
Rabbit
Immunogen:
Recombinant Human Merlin protein (230-414AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Protein G Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody