Skip to content

Warenkorb

Der Warenkorb ist leer.

Gesamt (exkl. MwSt.) £0,00
Warenkorb überprüfen & bezahlen
Antikörper

MOCS3 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA014707ESR2HU-50UL
100 ul
£334,00
CSB-PA014707ESR2HU-100UL
Über dieses Produkt
SKU:
CSB-PA014707ESR2HU
Zusätzliche Namen:
Adenylyltransferase MOCS3 antibody; dJ914P20.3 antibody; MGC9252 antibody; MOCS 3 antibody; MOCS3 antibody; MOCS3_HUMAN antibody; Molybdenum cofactor synthesis 3 antibody; Molybdenum cofactor synthesis protein 3 antibody; Molybdopterin synthase sulfurylase antibody; Molybdopterin-synthase sulfurtransferase antibody; MPT synthase sulfurylase antibody; Sulfur carrier protein MOCS2A adenylyltransferase antibody; Sulfur carrier protein MOCS2A sulfurtransferase antibody; Sulfurtransferase MOCS3 antibody; UBA 4 antibody; UBA4 ubiquitin activating enzyme E1 homolog antibody; UBA4 antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
Host:
Rabbit
Immunogen:
Recombinant Human Adenylyltransferase and sulfurtransferase MOCS3 protein (271-460AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody