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Antikörper

MLF1 Antibody

Produktgrößen
50 ul
£186,00
CSB-PA014621ESR1HU-50UL
100 ul
£334,00
CSB-PA014621ESR1HU-100UL
Über dieses Produkt
SKU:
CSB-PA014621ESR1HU
Zusätzliche Namen:
Hls7 antibody; MLF1 antibody; MLF1_HUMAN antibody; Myelodysplasia myeloid leukemia factor 1 antibody; Myelodysplasia-myeloid leukemia factor 1 antibody; Myeloid leukemia factor 1 antibody; myeloid leukemia factor 1 variant 1 antibody; myeloid leukemia factor 1 variant 2 antibody; myeloid leukemia factor 1 variant 3 antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Host:
Rabbit
Immunogen:
Recombinant Human Myeloid leukemia factor 1 protein (1-268AA)
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody