Loxl2 Antibody, Biotin conjugated
Produktgrößen
50 ug
£186,00
CSB-PA013041LD01MO-50UG
100 ug
£334,00
CSB-PA013041LD01MO-100UG
Über dieses Produkt
- SKU:
- CSB-PA013041LD01MO
- Zusätzliche Namen:
- Loxl2Lysyl oxidase homolog 2 antibody; EC 1.4.3.13 antibody; Lysyl oxidase-like protein 2 antibody
- Anwendung:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated Lys-4 of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3 By similarity. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
- Host:
- Rabbit
- Immunogen:
- Recombinant Mouse Lysyl oxidase homolog 2 protein (26-776AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:Loxl2-AntibodyBiotin-conjugated-1090699.html