KIDINS220 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA012306LA01HU-50UG
100 ug
£334,00
CSB-PA012306LA01HU-100UG
Über dieses Produkt
- SKU:
- CSB-PA012306LA01HU
- Zusätzliche Namen:
- Ankyrin repeat-rich membrane-spanning protein antibody; arms antibody; KDIS_HUMAN antibody; kidins220 antibody; Kinase D interacting substance of 220 kDa antibody; Kinase D-interacting substrate of 220 kDa antibody; rgd 619949 antibody
- Anwendung:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Kinase D-interacting substrate of 220 kDa protein (1077-1370AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:KIDINS220-Antibody-12553642.html
