Keap1 Antibody
Produktgrößen
50 ug
£186,00
CSB-PA012147LA01MO-50UG
100 ug
£334,00
CSB-PA012147LA01MO-100UG
Über dieses Produkt
- SKU:
- CSB-PA012147LA01MO
- Zusätzliche Namen:
- Keap1 antibody; Inrf2 antibody; Kiaa0132Kelch-like ECH-associated protein 1 antibody; Cytosolic inhibitor of Nrf2 antibody; INrf2 antibody
- Anwendung:
- ELISA, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Klonalität:
- Polyclonal
- Weitere Details:
- Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Mouse Kelch-like ECH-associated protein 1 protein (1-624AA)
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:Keap1-Antibody-11107768.html
