IRF8 Antibody

Produktgrößen

50 ul

£186,00

CSB-PA011823ESR1HU-50UL

100 ul

£334,00

CSB-PA011823ESR1HU-100UL

Über dieses Produkt

SKU:: CSB-PA011823ESR1HU
Zusätzliche Namen:: H ICSBP antibody; H-ICSBP antibody; HGNC:5358 antibody; HICSBP antibody; ICSBP 1 antibody; ICSBP antibody; ICSBP1 antibody; Interferon consensus sequence binding protein 1 antibody; Interferon consensus sequence binding protein antibody; Interferon consensus sequence-binding protein antibody; Interferon regulatory factor 8 antibody; IRF 8 antibody; IRF-8 antibody; Irf8 antibody; IRF8_HUMAN antibody; MYLS antibody
Anwendung:: ELISA, Immunohistochemistry
Buffer:: PBS
Klonalität:: Polyclonal
Weitere Details:: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.
Host:: Rabbit
Immunogen:: Recombinant Human Interferon regulatory factor 8 protein (137-426AA)
Isotyp:: IgG
Physischer Zustand:: Liquid
Aufreinigung:: Affinity Purified
Reaktivitäten:: Human
Versandbedingungen:: Blue Ice
Lagerbedingungen:: -20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:: Cusabio
Typ:: Antibody: Polyclonal Antibody

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